4,136 research outputs found

    N=2 Conformal Superspace in Four Dimensions

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    We develop the geometry of four dimensional N=2 superspace where the entire conformal algebra of SU(2,2|2) is realized linearly in the structure group rather than just the SL(2,C) x U(2)_R subgroup of Lorentz and R-symmetries, extending to N=2 our prior result for N=1 superspace. This formulation explicitly lifts to superspace the existing methods of the N=2 superconformal tensor calculus; at the same time the geometry, when degauged to SL(2,C) x U(2)_R, reproduces the existing formulation of N=2 conformal supergravity constructed by Howe.Comment: 43 pages; v2 references added, acknowledgments update

    Agronomic characteristics of the spring forms of the wheat landraces (einkorn, emmer, spelt, intermediate bread wheat) grown in organic farming

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    Organic farmers look to the possibilities of growing neglected crops, such as the spring forms of hulled wheat – einkorn, emmer and spelt – for support in developing the organic farming system. In 2008, 169 landraces from the gene bank at the Crop Research Institute in Prague were tested on certifi ed organic plots. The experiment was aimed at fi nding suitable varieties for the organic farming system. In summary, our fi ndings show that einkorn (Triticum monococcum L.) and emmer wheat [Triticum dicoccum Schrank (Schuebl)] are resistant to powdery mildew and brown rust, spelt wheat (Triticum spelta L.) is less resistant to these two diseases, and the intermediate forms of bread wheat are very sensitive to such infestation. The varieties evaluated incline to lodging, as they have long and weak stems. Einkorn and emmer wheat have short and dense spikes and a low thousand grains weight, whereas spelt wheat has long and lax spikes. The level of the harvest index is low. Potentially useful varieties were found during the fi eld experiment and evaluation, and our future efforts will therefore focus on improving resistance to lodging and increasing the productivity of the spike

    The Plasmodium falciparum, Nima-related kinase Pfnek-4: a marker for asexual parasites committed to sexual differentiation

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    <b>Background</b> Malaria parasites undergo, in the vertebrate host, a developmental switch from asexual replication to sexual differentiation leading to the formation of gametocytes, the only form able to survive in the mosquito vector. Regulation of the onset of the sexual phase remains largely unknown and represents an important gap in the understanding of the parasite's complex biology. <b>Methods:</b> The expression and function of the Nima-related kinase Pfnek-4 during the early sexual development of the human malaria parasite Plasmodium falciparum were investigated, using three types of transgenic Plasmodium falciparum 3D7 lines: (i) episomally expressing a Pfnek-4-GFP fusion protein under the control of its cognate pfnek-4 promoter; (ii) episomally expressing negative or positive selectable markers, yeast cytosine deaminase-uridyl phosphoribosyl transferase, or human dihydrofolate reductase, under the control of the pfnek-4 promoter; and (iii) lacking a functional pfnek-4 gene. Parasite transfectants were analysed by fluorescence microscopy and flow cytometry. In vitro growth rate and gametocyte formation were determined by Giemsa-stained blood smears. <b>Results:</b> The Pfnek-4-GFP protein was found to be expressed in stage II to V gametocytes and, unexpectedly, in a subset of asexual-stage parasites undergoing schizogony. Culture conditions stimulating gametocyte formation resulted in significant increase of this schizont subpopulation. Moreover, sorted asexual parasites expressing the Pfnek-4-GFP protein displayed elevated gametocyte formation when returned to in vitro culture in presence of fresh red blood cells, when compared to GFP- parasites from the same initial population. Negative selection of asexual parasites expressing pfnek-4 showed a marginal reduction in growth rate, whereas positive selection caused a marked reduction in parasitaemia, but was not sufficient to completely abolish proliferation. Pfnek-4- clones are not affected in their asexual growth and produced normal numbers of stage V gametocytes. <b>Conclusions:</b> The results indicate that Pfnek-4 is not strictly gametocyte-specific, and is expressed in a small subset of asexual parasites displaying high rate conversion to sexual development. Pfnek-4 is not required for erythrocytic schizogony and gametocytogenesis. This is the first study to report the use of a molecular marker for the sorting of sexually-committed schizont stage P. falciparum parasites, which opens the way to molecular characterization of this pre-differentiated subpopulation

    Defoliation of Tilia cordata trees associated with Apiognomonia errabunda infection in Finland

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    We investigated the causative agent of a disease outbreak affecting small-leaved limes (Tilia cordata Mill.) and resulting in darkening of the leaf petioles and excessive defoliation during summer 2016 in southern Finland. The fungal species composition of the symptomatic petioles was examined by culture isolation and molecular identification using ITS rDNA sequences, which revealed the most prevalent fungal species present in the petioles as Apiognomonia errabunda (Roberge) Hhn. Based on reviewing curated herbarium specimens deposited at the Universities of Helsinki and Turku, A. errabunda is native and widely distributed in small-leaved limes in Finland, and occasionally infects also other broadleaved trees, including Quercus robur L. and ornamental species of Tilia L. and Fagus L. The ITS sequence analysis conducted during this study revealed minor within-species polymorphisms similar to those observed earlier in the Central European and Russian populations of A. errabunda, and reports the first nucleotide sequences of this species from the Nordic countries

    Seebeck Effect in Magnetic Tunnel Junctions

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    Creating temperature gradients in magnetic nanostructures has resulted in a new research direction, i.e., the combination of magneto- and thermoelectric effects. Here, we demonstrate the observation of one important effect of this class: the magneto-Seebeck effect. It is observed when a magnetic configuration changes the charge based Seebeck coefficient. In particular, the Seebeck coefficient changes during the transition from a parallel to an antiparallel magnetic configuration in a tunnel junction. In that respect, it is the analog to the tunneling magnetoresistance. The Seebeck coefficients in parallel and antiparallel configuration are in the order of the voltages known from the charge-Seebeck effect. The size and sign of the effect can be controlled by the composition of the electrodes' atomic layers adjacent to the barrier and the temperature. Experimentally, we realized 8.8 % magneto-Seebeck effect, which results from a voltage change of about -8.7 {\mu}V/K from the antiparallel to the parallel direction close to the predicted value of -12.1 {\mu}V/K.Comment: 16 pages, 7 figures, 2 table

    CPT and Lorentz-invariance violation

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    The largest gap in our understanding of nature at the fundamental level is perhaps a unified description of gravity and quantum theory. Although there are currently a variety of theoretical approaches to this question, experimental research in this field is inhibited by the expected Planck-scale suppression of quantum-gravity effects. However, the breakdown of spacetime symmetries has recently been identified as a promising signal in this context: a number of models for underlying physics can accommodate minuscule Lorentz and CPT violation, and such effects are amenable to ultrahigh-precision tests. This presentation will give an overview of the subject. Topics such as motivations, the SME test framework, mechanisms for relativity breakdown, and experimental tests will be reviewed. Emphasis is given to observations involving antimatter.Comment: 6 page

    The effectiveness and satisfaction of web-based physiotherapy in people with spinal cord injury: a pilot randomised controlled trial

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    Study Design: Pilot randomised controlled trial. Objectives: The aims of this study were to evaluate the effectiveness and participant satisfaction of web-based physiotherapy for people with Spinal Cord Injury (SCI). Setting: Community patients of a national spinal injury unit in a university teaching hospital, Scotland, UK. Methods: Twenty-four participants were recruited and randomised to receive eight weeks of web-based physiotherapy (intervention), twice per week, or usual care (control). Individual exercise programmes were prescribed based upon participant’s abilities. The intervention was delivered via a website (www.webbasedphysio.com) and monitored and progressed remotely by the physiotherapist. Results: Participants logged on to the website an average of 1.4±0.8 times per week. Between-group differences, although not significant were more pronounced for the 6 minute walk test. Participants were positive about using web-based physiotherapy and stated they would be happy to use it again and would recommend it to others. Overall it was rated as either good or excellent. Conclusions: Web-based physiotherapy was feasible and acceptable for people with SCI. Participants achieved good compliance with the intervention, rated the programme highly and beneficial for health and well-being at various states post injury. The results of this study warrant further work with a more homogenous sample

    Quality Of Antenatal Care In Rural Southern Tanzania: A Reality Check.

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    Counselling on the danger signs of unpredictable obstetric complications and the appropriate management of such complications are crucial in reducing maternal mortality. The objectives of this study were to identify gaps in the provision of ANC services and knowledge of danger signs as well as the quality of care women receive in case of complications. The study took place in the Rufiji District of Tanzania in 2008 and was conducted in seven health facilities. The study used (1) observations from 63 antenatal care (ANC) sessions evaluated with an ANC checklist, (2) self-assessments of 11 Health workers, (3) interviews with 28 pregnant women and (4) follow-up of 12 women hospitalized for pregnancy-related conditions.Blood pressure measurements and abdominal examinations were common during ANC visits while urine testing for albumin or sugar or haemoglobin levels was rare which was often explained as due to a lack of supplies. The reasons for measuring blood pressure or abdominal examinations were usually not explained to the women. Only 15/28 (54%) women were able to mention at least one obstetric danger sign requiring medical attention. The outcomes of ten complicated cases were five stillbirths and three maternal complications. There was a considerable delay in first contact with a health professional or the start of timely interventions including checking vital signs, using a partograph, and detailed record keeping. Linking danger signs to clinical and laboratory examination results during ANC with the appropriate follow up and avoiding delays in emergency obstetric care are crucial to the delivery of coordinated, effective care interventions

    Problematic plate reconstruction

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    Author Posting. © The Author(s), 2012. This is the author's version of the work. It is posted here by permission of Nature Publishing Group for personal use, not for redistribution. The definitive version was published in Nature Geoscience 5 (2012): 676-677, doi:10.1038/ngeo1596.As has been previously proposed, Bronner et al. suggest that opening of the rift between Newfoundland and Iberia involved exhumation of mantle rocks until 112 million years ago, subsequent seafloor spreading, and crustal thickening along the high-amplitude J magnetic anomaly by magma that propagated from the Southeast Newfoundland Ridge area. Conventionally, the anomalous magnetism and basement ridges associated with the J anomaly north of the Newfoundland-Gibraltar Fracture Zone are thought to have formed about 125 million years ago at chron M0 (Fig. 1a), although the crust probably experienced some later magmatic overprinting. The M0 age would make their formation simultaneous with that of the similar J anomaly and basement ridges (the J Anomaly Ridge and Madeira Tore Rise) along the Mid-Atlantic Ridge to the south and place them within a zone of exhumed mantle in the Newfoundland-Iberia rift. In contrast, Bronner et al. propose that the J anomaly and associated basement ridges were formed by later magmatism (about 112 million years ago) that marked the end of mantle exhumation in the rift. We argue here that constraints from plate tectonic reconstructions render this possibility untenable.2013-04-0
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